Posner-Schlossman Syndrome

Posner Schlossman syndrome, also known as glaucomatocyclitic crisis, is an infrequently encountered cause of inflammatory ocular hypertension. It is characterized by recurrent episodes of uniocular rise in intraocular pressure, out of proportion with minimal intraocular inflammation.

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I had read about the Posner-Schlossman Syndrome and thought that much of the condition as described seemed to fit my experience and wondered if this were more the case for what I was experiencing than the psudeo exfoliation induced glaucoma for which I was diagnosed and was treated in the traditional ways.

Posner and Schlossman are the names of the researchers who first identified and described the syndrome in 1948. They first reported a series of 9 cases and given the name glaucomatocyclitic crisis to describe this condition.

If you are interested to find out more, here are the links that I found useful revealing a lot of information.

https://en.wikipedia.org/wiki/Posner%E2%80%93Schlossman_syndrome

https://prezi.com/o2ojlqz4sugu/posner-schlossman-syndrome/

https://eyewiki.aao.org/Glaucomatocyclitic_Crisis_(Posner-Schlossman_Syndrome)

https://www.ncbi.nlm.nih.gov/books/NBK576412/#:~:text=Posner%20Schlossman%20syndrome%2C%20also%20known,proportion%20with%20minimal%20intraocular%20inflammation.

https://pubmed.ncbi.nlm.nih.gov/33123397/#:~:text=Abstract,as%20potential%20etiologies%20of%20PSS.

Is Posner-Schlossman syndrome curable?

Posner-Schlossman Syndrome has long thought to be a “benign” disease; most patients are treated for attacks and recover without long-term sequelae. However, a number of patients with repeated attacks, even if treated, may show long term glaucomatous changes in the optic nerve and on visual field testing.

I discussed this matter at length with several opthamologists, all of whom were somewhat dismissive of the possibility that this was what I was experiencing, and I am convinced now that they are correct. Additionally, given that the treatment would be much the same anyway, the entire discussion seemed to be moot so I left it at that.

Conclusion: PSS remains a rare condition with uncertain etiology and no associated systemic conditions. PSS has been postulated to be linked to autoimmune conditions. CVID is associated with many autoimmune disorders including Sjogren's, rheumatoid arthritis, and colitis. There have been a few reported CVID-associated ocular diseases including granulomatous uveitis and conjunctivitis, chronic anterior uveitis, and birdshot retinopathy. We describe the first case of PSS in a patient with CVI

My personal struggle with high bouts of IOP continue and the following posts will cover the next chapters in this ongoing story.